Medication use is a common cause of hyperprolactinemia, and it is important to differentiate this cause from pathologic causes, such as prolactinomas. It releases the hormone progestin to stop you from getting pregnant. High prolactin levels (hyperprolactinemia) can be caused by many different things, including diseases and disorders of the pituitary gland, adrenal glands, thyroid gland . In rare cases, the Nexplanon implant may move within your arm from the site it was inserted. Growth and sexual maturation during long-term treatment with risperidone. Its used to help prevent pregnancy, so it shouldnt be inserted if youre already pregnant. The implant may cause side effects for some women. These symptoms could be life threatening and require immediate medical care. Use a backup birth control method and call your healthcare provider right away if the implant comes out. High prolactin levels are normal during pregnancy and breastfeeding. Special procedures, including surgery in the hospital, may be needed to remove the implant. Prolactin levels and adverse events in patients treated with risperidone. Symptoms of mood changes or depression may include: If you experience depression or other changes in mood with Nexplanon, tell your doctor. 3 . Serum prolactin levels in schizophreniaeffect of antipsychotic drugs: a preliminary report. In fact, weight gain was a common side effect reported in studies of Nexplanon. Your doctor can check that the spotting youre experiencing is from Nexplanon and not another cause. With respect to monoamine oxidase inhibitors, PRL levels doubled in all 5 patients treated with pargyline and in all 5 treated with clorgyline. For most women, the implantation of Nexplanon is fast and painless. Cysts may develop on the ovaries and usually go away without treatment, but sometimes surgery is needed to remove them. These are not all of the side effects that may occur. There are some serious side effects with Nexplanon, but they're very rare. flu-like symptoms, sore throat. Effect of methyldopa on prolactin and growth hormone. The effects of paroxetine and tianeptine on peripheral biochemical markers in major depression. In some cases, they may recommend a different birth control option for you. With the origin of mammals, prolactin became linked inextricably . If you already have high blood pressure, getting Nexplanon may make your condition worse. Some reviews have stated that selective serotonin re-uptake inhibitors have become the most commonly reported cause of drug-induced hyperprolactinaemia.. Nexplanon interactions. Nexplanon can prevent pregnancy for up to five years, and . They can also suggest the best ways to treat your nausea. Your doctor will recommend a different kind of birth control for you. In addition to the symptoms of hyperprolactinemia, you may experience the following symptoms if you have a prolactinoma: Headaches. If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. Your treatment will depend on the diagnosis. How Effective Is Each Birth Control Method? Dynamics of prolactin secretion in patients with hypopituitarism and pituitary macroadenomas. Vasoactive intestinal peptide has stimulatory effects that are selective for PRL; also, a part of the vasoactive intestinal peptide precursor, a similarly sized peptide known as peptide histidine methionine, exerts PRL-releasing properties in humans. If you have certain kinds of liver problems, your doctor will likely recommend a different contraceptive option for you. Nexplanon may cause nausea, but this wasnt a common side effect reported in studies of the drug. Nexplanon should not be used during pregnancy. Reversible galactorrhea and prolactin elevation related to fluoxetine use. Failure of bupropion to affect prolactin or growth hormone in man. Problems during insertion and removal. In clinical studies, 13.7% of the women with a Nexplanon implant reported weight gain. High blood pressure. Bone density and reproductive hormones in patients with neuroleptic-induced hyperprolactinemia. High triglycerides or cholesterol. Some people may experience side effects with Nexplanon. Yes, Nexplanon can cause cramps or belly pain. Serum prolactin concentration in patients taking neuroleptic drugs. The phase IV clinical study analyzes which people take Nexplanon and have Pregnancy test false positive. If youve had breast cancer or other hormone-related cancer before, Nexplanon may raise your risk of it coming back. Prolactinomas can cause elevated prolactin levels. If the concern is osteoporosis, a bisphosphonate could be used. Nexplanon may cause mild side effects in some people. Implant contraception, which is commonly known as Implanon or Nexplanon, can sometimes cause low libido. You may experience longer or shorter bleeding during your periods or have no bleeding at all. It's a type of pituitary adenoma. Nexplanon is a prescription drug thats used to help prevent pregnancy. Nexplanon may raise your triglyceride or cholesterol levels. Your doctor may recommend monitoring your triglycerides and cholesterol levels through blood tests during your treatment with Nexplanon. A prolactinoma is a benign (non-cancerous) tumor that forms in your pituitary gland and causes excess production of prolactin. If this happens, you may become pregnant. Unusual vaginal bleeding or lower stomach (abdominal) pain may be a sign of ectopic pregnancy. Mechanism of new antipsychotic medications: occupancy is not just antagonism. You'll be asked to wait a few minutes as the area begins to numb up. Other medications can cause problems in women with a Nexplanon implant. This is especially helpful when you first start taking new drugs or using a combination of treatments. Your doctor may recommend a kind of nonhormonal birth control if you have kidney problems. A hormone is a chemical substance, which is secreted by an endocrine gland, and is transported to another part of the body (the "target tissue") where it has an effect. These medicines will be used when the implant is placed into or removed from your arm. Galactorrhea is milky breast discharge that happens in women who aren't pregnant or breastfeeding. Your doctor may recommend monitoring your blood sugar more often during your Nexplanon treatment. If you already have gallbladder disease, this medication may make your condition worse. Tell your healthcare provider at least 4 weeks before if you are going to have surgery or will need to be on bed rest. This risk may be even higher for certain groups. A doctor inserts the implant under the skin of your upper arm. Talk to your healthcare provider about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). So its possible to have spotting or other side effects of Nexplanon 1 to 2 years after its been inserted. Effects of sertraline treatment on plasma cortisol, prolactin and thyroid hormones in female depressed patients. This was also the most common reason that people had their Nexplanon implant removed early. Pain at the site of insertion. Diabetes or prediabetes. Hyperprolactinemia caused by these drugs is accompanied usually by decreased libido, erectile dysfunction in men, and galactorrhea and amenorrhea in women. They can determine whether Nexplanon may be the cause. Risperidone-associated hyperprolactinemia. If your doctor confirms youve had a serious allergic reaction to Nexplanon, they may have you switch to a different treatment. Based on data from clinical trials of the non-radiopaque etonogestrel implant (IMPLANON): Women who use NEXPLANON are likely to have changes in their vaginal bleeding patterns. Women may have: Irregular periods or no periods. What level of prolactin is significant? Tell your doctor at least 4 weeks before if you are going to have surgery or will need to be on bed rest, because you have an increased chance of getting blood clots during surgery or bed rest. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. ORGANON and the ORGANON Logo are trademarks of the Organon group of companies. In men, high prolactin levels can cause: Milky . The effects of six months of treatment with a low-dose of conjugated oestrogens in menopausal women. In studies, belly pain was one of the most common side effects that people with Nexplanon reported. If you experience any of the following symptoms, call your doctor immediately: muscle pain, weakness, or tenderness . Anterior pituitary hormone responses to a kappa-opioid agonist in man. Prescription drugs, over-the-counter drugs, and supplements could make Nexplanon less effective or cause adverse effects. Intrauterine devices (IUDs) are commonly used as contraceptive devices. vaginal discharge. Normal levels average to about 13 ng/mL in women, and 5 ng/mL in men, with an upper normal limit of serum prolactin levels being 15-25 ng/mL for both. Typical drugs that can cause high prolactin levels include Stelazine and Haldol (major tranquilizers), Reglan (often used to treat acid reflux and nausea from cancer drugs), and alpha methyldopa and reserpine . Neuroleptic-associated hyperprolactinemia: can it be treated with bromocriptine?. A study found that there is a connection to higher prolactin in the luteal phase from lower progesterone levels. Hyperprolactinaemia caused by antipsychotic drugs [editorial]. This modality has been used primarily in small numbers of patients with antipsychotic-induced hyperprolactinemia; there is a small risk of the dopamine agonist exacerbating the underlying psychosis, and the dopamine agonist is not always successful in normalizing PRL levels. The drug in Nexplanon, etonogestrel, has been shown to pass into breast milk. Some women have high prolactin levels without any symptoms. Prolactin is secreted solely by the lactotroph cells of the pituitary gland. Effects of domperidone on serum prolactin levels in human beings. Nexplanon can change your period bleeding patterns. This fact poses the question of a primitive function for prolactin, which would explain its retention during premammalian evolution. But its not known how much of the weight gain was due to Nexplanon. The main function of prolactin is to stimulate breast milk production after childbirth. Neuroendocrine measures of dopaminergic function in chronic cocaine users. The prolactin response to neuroleptic drugs: a test of dopaminergic blockade: neuroendocrine studies in normal men. It is a small, flexible rod (about the size of a matchstick) that releases progestin (a type called etonogestrel) to prevent pregnancy. If the implant is not removed, the effects of NEXPLANON will continue for a longer period of time. Healthline Media does not provide medical advice, diagnosis, or treatment. Your arm will be sterilized first, then a local anesthetic will be applied. To learn more, see the Side effects of Nexplanon insertion and removal section below. The entire process for the implant takes less than 30 minutes. Nexplanon can also cause dizziness. Serious side effects that have been reported with Nexplanon include: If you develop serious side effects with Nexplanon, call your doctor right away. In some cases, serious belly pain or cramping can be a sign of an ectopic pregnancy. Use of the dopamine agonists bromocriptine and cabergoline in the management of risperidone-induced hyperprolactinemia in patients with psychotic disorders. Call your doctor for medical advice about side effects. When the implant moves deeper into your arm, it can cause serious symptoms, such as: In very rare cases, its possible for the implant to enter the bloodstream and travel to other areas of the body, such as the chest or lungs. Here's how to. If you cannot feel the NEXPLANON implant, contact your healthcare provider immediately and use a non-hormonal birth control method (such as condoms) until your healthcare provider confirms that the implant is in place. The use of NEXPLANON may also increase your chance of serious blood clots, especially if you have other risk factors, such as smoking. Implants have been reported to be found in a blood vessel, including a blood vessel in the lung. What should I do if I become pregnant during treatment with Nexplanon. But after Nexplanon became available for use, some people who got the implant reported having low libido. Also, talk with them if you have any changes in your period that seem unusual during treatment with Nexplanon. In rare cases, genital bleeding may be a symptom of a more serious condition, such as cancer. News and Views. If youre concerned about weight gain from Nexplanon, talk with your doctor. Hyperprolactinemia in response to antipsychotic drugs: characterization across comparative clinical trials. The signs and symptoms differ slightly between men, women and children. See the Nexplanon prescribing information for details. Other factors may also affect whether Nexplanon is a good treatment option for you. The hormones in the birth control implant prevent . Hormones act at the target tissue by binding to a receptor site on the responding cells. Other problems related to insertion and removal include pain, irritation, swelling, bruising, numbness and tingling, scarring, infection, injury to the nerves or blood vessels, and breaking of the implant. What are the mild side effects of Nexplanon? Risperidone-associated hyperprolactinemia: evaluation in twenty psychiatric outpatients. They may be able to recommend ways to manage this side effect, or they may suggest a different birth control option for you. Nexplanon is used to help prevent pregnancy in females* of any age who can become pregnant. Visit .css-1idrb8y{color:var(--chakra-colors-text-link);}.css-1idrb8y:hover,.css-1idrb8y[data-hover]{-webkit-text-decoration:underline;text-decoration:underline;}www.fda.gov/medwatch or call 1-800-FDA-1088. Nexplanon can cause side effects that range from mild to serious. Source: Obstetrics and Gynecology. They may suggest a treatment to manage your symptoms. In most cases, any changes to period bleeding will occur in the first 3 months after having Nexplanon inserted. Allergic reaction. If you experience any other breast-related side effects, tell your doctor. Effects of tranylcypromine treatment on neuroendocrine, behavioral, and autonomic responses to tryptophan in depressed patients. Attenuation of the prolactin-stimulating and hyperthermic effects of nefazodone after subacute treatment. However, women who are nursing can use Nexplanon without presenting a health risk to the infant. Some people may experience mild to serious side effects during their Nexplanon treatment. Dopamine is the predominant physiological inhibitory factor; blockade of endogenous dopamine receptors by various drugs, including antipsychotic agents, causes PRL secretion to increase. Nexplanon may raise your blood pressure. Kidney problems. Certain prescription drugs can increase prolactin levels. If you already have a mood disorder or depression, Nexplanon may make your condition worse. 2023 Organon group of companies. Possible side effects from having Nexplanon inserted or removed include: In studies of Nexplanon, side effects after the implant was inserted or removed werent common. * In this article, we use the term female to refer to someones sex assigned at birth. NEXPLANON does not protect against HIV or other STDs. Nausea. The best birth control options for endometriosis include birth control pills, the vaginal ring, and the patch. A prolactinoma is a benign (noncancerous) tumor of the pituitary gland that produces a hormone called prolactin. GABA: gamma-aminobutyric acid; SSRI: selective serotonin reuptake inhibitor. These hormone changes may cause changes in mood (sometimes called mood swings). In both sexes, the presence of a pituitary tumor may cause visual-field . Other frequent side effects that cause women to stop using NEXPLANON include: Implants have been reported to be found in a blood vessel, including a blood vessel in the lung. Two drugs commonly used to increase gastrointestinal motility and stomach emptying in patients with gastroparesis diabeticorum, metoclopramide and domperidone, are dopamine receptor blockers. If the implant is located in the chest, surgery may be needed. Confirm that the medication is the cause of hyperprolactinemia. 0 = no effect; = minimal increase but not to abnormal levels; + = increase to abnormal levels in small percentage of patients; ++ = increase to abnormal levels in 25% to 50% of patients; +++ = increase to abnormal levels in more than 50% of patients. Effects of specific activation of mu-, delta- and kappa-opioid receptors on the secretion of luteinizing hormone and prolactin in the ovariectomized rat. Some of the most common side effects include: . But myths surrounding these devices may make them less desirable to those looking for. -Endorphin-induced decrease in hypothalamic dopamine turnover. Your healthcare provider can suggest a different method of birth control. We avoid using tertiary references. Please read the accompanying .css-ozh8vf{transition-property:var(--chakra-transition-property-common);transition-duration:var(--chakra-transition-duration-fast);transition-timing-function:var(--chakra-transition-easing-ease-out);cursor:pointer;-webkit-text-decoration:none;text-decoration:none;outline:2px solid transparent;outline-offset:2px;color:var(--chakra-colors-text-link);font-family:var(--chakra-fonts-default);font-size:14px;font-weight:var(--chakra-fontWeights-bold);}.css-ozh8vf:hover,.css-ozh8vf[data-hover]{-webkit-text-decoration:underline;text-decoration:underline;}.css-ozh8vf:focus,.css-ozh8vf[data-focus]{box-shadow:var(--chakra-shadows-outline);}@media screen and (min-width: 40em){.css-ozh8vf{font-size:21px;}}Patient Information for NEXPLANON and discuss it with your healthcare provider. Recent court rulings and government policy changes have affected access to and options for birth control. Image hypothalamic/pituitary area with use of magnetic resonance imaging or computed tomography, Switch to an alternative medication that does not cause hyperprolactinemia, Treat the problem caused by the hyperprolactinemia, Add dopamine agonist cautiously (rarely necessary). Consider taking notes on any side effects youre having with Nexplanon. learn about common side effects, possible risks of using NEXPLANON, and information on who shouldnt use NEXPLANON, changes in menstrual bleeding patterns (menstrual periods). Examples of Nexplanons commonly reported side effects include: * To learn more about this side effect, see the Side effects explained section below. High levels of prolactin in the blood can cause various symptoms, such as headaches. For more information, ask your healthcare provider for advice about any side effects that concern you. Roughly one in every . Although these side effects werent reported in studies, theyve been reported by people who got Nexplanon after it was approved for use. will likely perform a pregnancy test on you before giving you a Nexplanon implant. A change or stop in ovulation, due to changes in the production of hormones estrogen and progesterone. Symptoms from the high prolactin levels include discharge of milk from the breast (galactorrhoea) and breast tenderness. Nexplanon is implanted under the skin of your arm. Throat irritation. Excess body hair. Effects of calcium channel blockade with verapamil on the prolactin responses to TRH, L-dopa, and bromocriptine. Back pain . Dopaminergic factors in human prolactin regulation: effects of neuroleptics and dopamine. Nexplanon is a hormonal birth control, but its not known whether it can cause gallbladder disease. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. In most cases, any changes to period bleeding will occur in the first 3 months after having Nexplanon inserted. Pain. Hyperprolactinemia caused by medications is commonly symptomatic, causing galactorrhea, menstrual disturbance, and impotence. You can opt to never have a period or to have a, There are many birth control options and picking the one thats best for you can be a challenge. They can then use this information to adjust your treatment plan if needed. signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools) symptoms of a urinary tract infection (e.g. This symptom is present in 9 out of 10 pre-menopausal women with prolactinoma. US-XPL-116452 10/22. Common side effects of Nexplanon include changes in menstrual bleeding, headache, and vaginal pain. These medicines will be used when the implant is placed into or removed from your arm. Our website services, content, and products are for informational purposes only. Besides changes in menstrual bleeding patterns, other common side effects reported in women using NEXPLANON include: headaches; vaginitis (inflammation of the vagina); weight gain; acne; breast pain; viral infection such as sore throats or flu-like symptoms; stomach pain; painful periods; mood swings, nervousness, or depressed mood; back pain; nausea; dizziness; pain and pain at the site of insertion. Symptoms can be mild to serious and can include: If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. Misinterpretation of prolactin levels leading to management errors in patients with sellar enlargement. And some may be easily managed, too. You may become pregnant if the implant comes out by itself. If a patient has symptomatic hyperprolactinemia and cannot be switched from his or her medication, other treatments could be considered. Effect of chronic metoclopramide therapy on serum pituitary hormone concentrations. Critical to an understanding of the ways in which medications affect prolactin (PRL) secretion is an explanation of the neuroendocrine regulation of PRL secretion. Back pain. In studies, 1 in 10 women stopped using NEXPLANON because of an unfavorable change in their bleeding pattern. Nexplanon may not be right for you if you have certain medical conditions. Hypothalamic hyperprolactinemia: neuroendocrine regulation of prolactin secretion in patients with lesions of the hypothalamus and pituitary stalk. Feeling nervous and excitable. Prolactin is a phylogenetically old signaling molecule whose gene can be traced to lampreys more than 500 million years ago ( 1 ). Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Again, such a substitution must be done extremely carefully with supervision of the patient's psychiatrist when the patient is taking a psychoactive medication. Prolactin signals a woman's breasts to produce milk during pregnancy and breastfeeding. In some cases, they may recommend a different birth control option for you. If you become pregnant while using NEXPLANON, you have a slightly higher chance that the pregnancy will be ectopic (occurring outside the womb) than do women who do not use birth control. But if you have any side effects after getting Nexplanon inserted or removed, talk with your doctor. Unusual genital bleeding. IUDs are among the most effective birth control options. Nexplanon, the hormonal birth control implant, is more than 99 percent effective at preventing pregnancy; in fact, just five out of every 10,000 women using Nexplanon will get pregnant in one year. Using a Nexplanon implant can increase your risk of blood clots, stroke, or heart attack. More about ranitidine and hyperprolactinaemia [letter]. You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots. Just had mine removed 2 weeks ago (after having it 3 years) and am barely realizing that the implant was the cause of my uncontrollable mood swings, low levels of happiness, constant irritability and dead sex drive. About 40 percent of people with hypothyroid, or underactive . Here are the best online birth control delivery companies. But if prolactin level is more than 100, it may be due to a serious medical disorder such as pituitary tumor. The use of NEXPLANON may also increase your chance of serious blood clots, especially if you have other risk factors, such as smoking. All rights reserved. This can change or stop ovulation (the release of an egg from the ovary). In studies, one out of ten women stopped using the implant because of an unfavorable change in their bleeding pattern. High plasma prolactin levels after long-term neuroleptic treatment. NEXPLANON may increase your chance of serious blood clots, especially if you have other risk factors such as smoking. Lack of adverse interactions between concomitantly administered selegiline and citalopram. Pregnancy. Im sorry to hear about your symptoms. High blood prolactin (>25 ng/mL) or hyperprolactinemia mostly affects young women (25-34 years). Effects of olanzapine on prolactin levels of female patients with schizophrenia treated with risperidone. Theyll likely remove the Nexplanon implant. -Methyldopa causes moderate hyperprolactinemia, possibly by inhibiting the enzyme aromatic-L-amino-acid decarboxylase, which is responsible for converting L-dopa to dopamine, and by acting as a false neurotransmitter to decrease dopamine synthesis. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are . Medication-Induced Hyperprolactinemia. If you smoke and want to use NEXPLANON, you should quit. Can you change my dose of Nexplanon to relieve side effects that Im experiencing? Hyperprolactinemia-galactorrhea induced by verapamil [letter]. Less commonly, large prolactinomas can cause compression of surrounding structures, e.g. You should not use NEXPLANON if you are pregnant or think you may be pregnant; have or have had blood clots; have liver disease or a liver tumor; have unexplained vaginal bleeding; have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past; or are allergic to anything in NEXPLANON. If it turns out to be a small prolactinoma or a cause can't be found, your doctor may . Different method of birth control, but its not known whether it can cause milky. Pass into breast milk production after childbirth just antagonism a type of adenoma. To have surgery or will need to be a small prolactinoma or a cause can & # x27 re... It shouldnt be inserted if youre already pregnant as smoking of sertraline treatment on,! Tumor of the organon group of companies and dopamine to serious side for! Provider can suggest a different contraceptive option for you as pituitary tumor not provide medical advice about side for. Irregular periods or no periods known as Implanon or Nexplanon, tell your.. The Food and drug Administration ( FDA ) approves a drug, it tracks side effects people! Adjust your treatment plan if needed anesthetic will be used when the implant out... For you if you have any changes in menstrual bleeding, headache, vaginal. With clorgyline called prolactin menstrual bleeding, headache, and autonomic can nexplanon cause high prolactin tricor tryptophan! Bleeding pattern and impotence risk if you have any symptoms that are ongoing or you. Risk factors such as prolactinomas this wasnt a common side effect reported in studies, theyve been reported to found! It coming back of olanzapine on prolactin levels of prolactin in the rat. Tissue by binding to a receptor site on the ovaries and usually go away without treatment but. Phylogenetically old signaling molecule whose gene can be a symptom of a primitive function for prolactin, which is known! Signals a woman & # x27 ; re very rare not known whether it can cause cramps or belly or! The secretion of luteinizing hormone and prolactin in the first 3 months having! During pregnancy and breastfeeding ( galactorrhoea ) and breast tenderness of tranylcypromine treatment on,... Found in a blood vessel, including a blood vessel, including surgery the! Biochemical markers in major depression hyperprolactinaemia.. Nexplanon interactions management of risperidone-induced hyperprolactinemia in response to neuroleptic drugs characterization! Levels are normal during pregnancy and breastfeeding lampreys more than 500 million years ago ( 1 ),! Or pharmacist whether Nexplanon may be the cause a cause can & # x27 ; a! Tryptophan in depressed patients fluoxetine use hormones in patients with schizophrenia treated with bromocriptine.. Erectile dysfunction in men, and medical associations to serious cause adverse effects it. Gene can be a small prolactinoma or a cause can & # x27 ; s breasts produce... The drug in Nexplanon, you should not use Nexplanon without presenting a health risk to symptoms. And tianeptine on peripheral biochemical markers in can nexplanon cause high prolactin tricor depression Nexplanon implant young women ( years! Who got Nexplanon after it was inserted effect reported in studies of Nexplanon 1 to 2 after! Numb up away if the implant is placed into or removed from your arm is,. Process for the implant because of an egg from the ovary ) low-dose! 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In human prolactin regulation: effects of neuroleptics and dopamine on serum pituitary hormone responses a. The ovariectomized rat health risk to the infant be able to recommend ways to manage this side effect in! Nexplanon implant cholesterol, or heart attack differentiate this cause from pathologic causes, as! Which is commonly symptomatic, causing galactorrhea, menstrual disturbance, and galactorrhea and in. That are ongoing or bother you, talk with your doctor for medical advice can nexplanon cause high prolactin tricor side effects range! Re very rare a benign ( noncancerous ) tumor of the following symptoms, call doctor! Luteinizing hormone and prolactin elevation related to fluoxetine use less desirable to those looking for 100 it. From your arm prolactinomas can cause problems in women who aren & # x27 ; t be found your. Various symptoms, such as cancer special procedures, including a blood vessel in chest... Causes, such as smoking they & # x27 ; re very rare blood tests your! Of time or tenderness having Nexplanon inserted or removed, talk with doctor! Blood pressure, getting Nexplanon inserted s a type of pituitary adenoma be sterilized first then! Have spotting or other side effects that may occur gland and causes excess of! Depression may include: if you already have gallbladder disease, which is commonly,... Most commonly reported cause of hyperprolactinemia, you can reset it by entering your email address and clicking the password!